What are the Side Effects of CBD Oil?
As a responsible consumer, you’re likely curious of whether there are any side effects of cannabidiol (CBD) oil. We understand that you want to know how CBD oil will make you feel and any effects it could have before you incorporate the supplement into your and your family’s daily nutritional routine.
No Psychoactive High
First, it’s important to understand that experiencing a euphoric effect, or “high,” is not a side effect of CBD oil. Because CBD oil comes from cannabis (hemp), a common misconception is that it is psychoactive. The truth is, while both hemp and marijuana are cannabis plants they have different levels of tetrahydrocannabinol (THC), the well-known psychoactive cannabinoid. Unlike medical marijuana products, CBD oil that’s derived from hemp contains only trace amounts of THC.
CBD oil is therefore completely non-psychoactive. This means that CBD, as opposed to THC, will not adversely affect:
- Sensory awareness
- Reaction time
So what is CBD oil? Hemp CBD oil is derived from hemp, a type of cannabis that contains only up to 0.3 percent THC — nearly 33 times less than the least potent marijuana.
CBD even has anti-psychoactive properties, making it capable of countering the euphoric effects of the psychoactive cannabinoid, tetrahydrocannabinol (THC). THC elicits a high by binding with the endocannabinoid system’s cannabinoid 1 receptor (CB1), but CBD blocks the receptor and prevents it from binding with THC.
What Side Effects Does CBD Have?
Derived from cannabis plants like hemp, cannabinoids such as CBD interact with your native endocannabinoid system. This central system’s responsibility is to maintain the body’s homeostasis for a wide array of systems, including sleep, mood, mentality, appetite, immune response and more. Each day, our outside environment influences your systems, causing them to fluctuate. The endocannabinoid system is constantly working to keep them in balance. CBD and other cannabinoids support the efforts of this naturally occurring endocannabinoid system.
CBD is thought to be well-tolerated and safe for human consumption and has few side effects. According to WebMD, “CBD doses of up to 300 mg daily have been used safely for up to 6 months. Higher doses of 1200-1500 mg daily have been used safely for up to 4 weeks.” There have been some reports of dry mouth, low blood pressure, lightheadedness, and drowsiness, the health information site reports.
A research review investigating CBD side effects and safety found that CBD had no adverse physiological side effects on the following:
- Blood pressure
- Heart rate
- Body temperature
- Glucose levels
- pH levels
- Exchange of oxygen and carbon dioxide between the lungs and bloodstream
- Red blood cell volume
- Time it takes for food to leave stomach and travel through the intestines
- Vomiting action
- Potassium and sodium levels
CBD Oil Side Effects on Medication
Some evidence suggests that the CBD found in CBD oil can influence the way some medications are broken down in the body. Specifically, CBD interacts with the liver’s cytochrome P450 enzymatic system that is responsible for metabolizing many of the most-commonly prescribed medications.
There is some evidence that when CBD is taken at sufficient servings, the compound can temporarily deactivate P450 enzymes by occupying the site of enzymatic activity. This may prevent the enzyme family from metabolizing other compounds, allowing them to accumulate in the bloodstream over time and either making them more active, or potent.
More than 90 percent of medications are metabolized by the P450 enzymatic system. While more research is needed into how CBD oil affects the enzyme family, some of the more common over-the-counter and prescription drugs that may be impacted by taking CBD oil include acetaminophen, antibiotics, antihistamines, antidepressants, anti-epileptics, steroids, and beta blockers.
In general, it’s a good rule of thumb to check with your physician before taking CBD oil if you’re already taking other medications. Your doctor may want to check and monitor your blood levels to see if CBD oil is having any influence on how your liver breaks down other medications. They may decide to adjust the dosages of the drugs you’re taking to account of the side effects of CBD oil on the P450 enzyme group.
Daily Servings That Work For You
While there are no known adverse CBD oil side effects and it’s shown to be well tolerated even at higher doses, when starting a new CBD oil supplement routine it is suggested that you start with a low potency and gradually increase your intake of CBD as you best see fit. This will help you dial in the daily CBD serving that works best for you and identify any side effects you might experience early on.
Once you figure out the CBD levels you’d like to obtain each day, begin below that number. Start with a few drops daily or a product containing lower milligrams. Every week, gradually work your way up and monitor how you feel.
When you reach your ideal daily serving size, you can then decide whether to stay where you are or to continue increasing. This method will help you find the right serving of CBD that’s best for your own endocannabinoid system. Learn more about how to choose the right dosage of CBD oil.
Other Considerations Related to CBD Oil Side Effects
While the side effects of CBD oil have shown to be minimal and not common, it is important to keep in mind that not all CBD oil products share the same quality and safety standards. Now that CBD oil is hot in demand, new manufacturers and products have flooded the market. There is concern that some of the CBD oil products available are unreliable in their purity and CBD content. As a bioaccumulator, hemp absorbs compounds and substances from the soil. CBD oil products sourced from hemp grown with chemical fertilizers, herbicides, and pesticides can be contaminated. CBD oil contaminated with pesticides can potentially lead to side effects like headache, fatigue, dizziness, loss of appetite with nausea, stomach cramps, and diarrhea.
Additionally, a manufacturer may opt to use a potentially toxic chemical solvents to extract the oil. CBD oil contaminated with the commonly-used extract butane can lead to side effects like headache, vomiting, diarrhea, and confusion. Swallowing CBD oil contaminated with the solvent hexane can lead to severe abdominal pain and may impact the respiratory system.
To avoid experiencing contaminated CBD oil side effects, it is important to only buy high-quality CBD oil products from companies you trust. Medical Marijuana, Inc. sources our hemp from a collective of 750 family farms in the Netherlands, who grow the plants without any chemical fertilizers, herbicides, or pesticides that can contaminate our CBD supplements. We use a safe and non-toxic supercritical CO2 process to pull the CBD oil from the plant, and then rigorously test our CBD oil products three separate times through our Triple Lab Tested® process.
Learn More About CBD Oil
Medical Marijuana, Inc. is here to separate the CBD myths from the facts, and we also offer a wide array of CBD oil products, including pure hemp oil, liquids, tinctures, and capsules– we even offer CBD for pets.